Abstract:Background: A significant factor in blindness is primary angle closure glaucoma (PACG). With the new development of optical coherence tomography angiography (OCTA), we may be able to better understand how the integrity of the microvasculature affects the etiology of glaucoma. This work’s aim is to assess disc perfusion, neuronal structure, and visual field abnormalities, as well as the papillary and peripapillary the retinal vascular density (VD) in eyes with primary acute angle closure crisis (PAACC).
Methods: The case control study had been carried out on 40 eyes of 20 patients with unilateral PAACC and served as the case group with the contralateral eye has no symptoms or signs suggesting a previous attack and served as the control group.
Results: In relation to the best corrected visual acuity (BCVA), intraocular pressure (IOP), visual field (VF) mean deviation (decibels), the retinal nerve fiber layer (RNFL) thickness (m), ganglion cells complex (GCC) thickness (m), vertical cup-to-disc ratio (VCDR), inside disc vessel density (IVD), and all quadrants—with the exception of the nasal quadrant—a statistically substantial variance was existed between both groups. When contrasted with the control group, the PACG's all vessel density and structural measurements were considerably lower. Glaucomatous eyes have much lower papillary and Peripapillary VD than normal ones. The peripapillary plexus was significantly associated with RNFL, MD, VCDR, and GCC.
Conclusions: In glaucomatous eyes with RNFL and GCC thinning, OCTA is an effective tool for diagnosing vascular modifications. When compared to the opposite normal eyes, papillary and peripapillary retinal VD dramatically reduced in acute PACG eyes. There was a substantial association between various glaucomatous modifications and peripapillary retinal VD.
