International Journal of Medical Ophthalmology
Login   Signup

Vol. 5 Issue 1 Part A

2023, Vol. 5 Issue 1, Part A
Relation between quantitative measurement of the foveal avascular zone, outer retinal layers disruptions, and visual acuity in diabetic macular ischemia
Author(s): Shimaa Elmoselhy Abd Elmawla, Raouf Ahmed GA, Hammouda Hamdy Ghoraba and Mohamed Hosny El-Bradey
Abstract:
Background: With the potential to offer more in-depth images of the macula than foveal avascular (FA) imaging, optical coherence tomography angiography (OCTA) is emerging as a novel imaging tool for the detection of diabetic macular ischemia (DMI). The study's goal was to determine the relationship between visual acuity (VA) in DMI, foveal avascular zone (FAZ) and retinal vessel density (VD) as measured by OCTA, and the integrity of the outer retinal layers as measured by optical coherence tomography angiography (OCT).
Methods: This a cross sectional research enrolled 25 eyes of 25 diabetic cases diagnosed with DMI using FFA, and 25 normal eyes as a control group. All cases underwent ocular exam including VA testing, anterior segment exam, intra ocular pressure, fundus exam, and fundus fluorescein angiography (FFA).
Results: Reduction of vision was noticed in ischemic cases, the mean BCVA for the cases was 0.88±0.27 (LogMAR), while for the control was 0.03±0.04. A statistically prominent positive relation was detected between best corrected visual acuity (BCVA) (LogMAR) and (FAZ) area (rs=0.530, P=0.006), a statistically prominent negative relation was detected between BCVA (LoMAR) and both vessel area density (VAD) parameters (SCP and DCP) (VADSCP: rs= -0.415, P=0.039) (VADDCP: rs = -0.525, P =0.007).
Conclusions: OCTA allows for the quick, automated, and non-invasive quantification of vascular density and FAZ in DMI.
Pages: 47-53  |  263 Views  100 Downloads
Download Full Article: Click Here
How to cite this article:
Shimaa Elmoselhy Abd Elmawla, Raouf Ahmed GA, Hammouda Hamdy Ghoraba, Mohamed Hosny El-Bradey. Relation between quantitative measurement of the foveal avascular zone, outer retinal layers disruptions, and visual acuity in diabetic macular ischemia. Int J Med Ophthalmol 2023;5(1):47-53. DOI: 10.33545/26638266.2023.v5.i1a.139
International Journal of Medical Ophthalmology

International Journal of Medical Ophthalmology

 
International Journal of Medical Ophthalmology
Call for book chapter