Abstract:Introduction: This prospective study aimed to evaluate the effectiveness of pan retinal photocoagulation (PRP) in the management of proliferative diabetic retinopathy (PDR) over a one-year follow-up period. The study explored various factors influencing visual outcomes in PDR patients and assessed the safety and efficacy of PRP.
Materials and Methods: A total of 130 eyes from 90 patients with PDR received PRP during the study period. Follow-up was conducted for one year. Baseline parameters, including best-corrected visual acuity, intraocular pressure, slit-lamp examination, and retinal examination, were assessed. The study considered the duration of diabetes, pre-treatment visual acuity, age, glycemic control, hypertension, nephropathy, and other relevant factors as determinants of visual prognosis.
Results: Duration of diabetes significantly impacted visual outcomes, with shorter durations associated with better prognosis. Good pre-treatment visual acuity and younger patient age were positive predictors of visual improvement post-PRP. Glycemic control emerged as a critical factor, with high blood glucose levels increasing the risk of PDR. Hypertension and nephropathy were identified as significant risk factors for decreased vision in PDR subjects. PRP was a safe and effective method for controlling diabetic retinopathy, reducing the risk of severe vision loss by 50%. Encouraging regression of new vessels was observed in PDR patients following PRP treatment.
Conclusion: This prospective study underscores the significance of timely and aggressive intervention in PDR management. PRP is a safe and effective treatment, and its success is influenced by factors such as duration of diabetes, pre-treatment visual acuity, age, glycemic control, hypertension, and nephropathy.